Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | SCARB1 | Q8WTV0 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MPC2 | O95563 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778666 | 0.88 | FFAR1 (0.48) | FFAR1PPARAALDH1A1NPSR1HDAC6 | |
| SCHEMBL13846783 | 0.85 | HDAC1 (0.48) | FFAR1PPARAALDH1A1HDAC6HDAC1 | |
| SCHEMBL4778234 | 0.82 | KDM4E (0.53) | FFAR1PPARAALDH1A1NPSR1PPARG | |
| SCHEMBL4780233 | 0.81 | HDAC6 (0.43) | FFAR1PPARAALDH1A1NPSR1HDAC6 | |
| SCHEMBL100284 | 0.79 | FFAR1 (0.50) | FFAR1PPARAALDH1A1NPSR1PPARG | |
| SCHEMBL212000 | 0.79 | PPARG (0.62) | FFAR1PPARAALDH1A1NPSR1PPARG | |
| SCHEMBL1002975 | 0.79 | HDAC6 (0.67) | HDAC6HDAC1HDAC10CNR2HDAC3 | |
| SCHEMBL5324367 | 0.77 | PPARG (0.50) | FFAR1PPARAALDH1A1NPSR1PPARG | |
| SCHEMBL4101347 | 0.76 | HDAC6 (0.51) | HDAC6HDAC1HDAC10HDAC3 | |
| SCHEMBL5438238 | 0.76 | P2RX4 (0.66) | HDAC6HDAC1HDAC10CNR2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |