Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | MPC2 | O95563 | 1/20 | 0.43 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4779539 | 0.91 | CA2 (0.53) | PPARGP2RX4ALDH1A1NPSR1MAPT | |
| SCHEMBL4778666 | 0.82 | FFAR1 (0.48) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL4778234 | 0.81 | KDM4E (0.53) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL4781441 | 0.80 | PTPN1 (0.52) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL5322829 | 0.77 | FFAR1 (0.45) | PPARGALDH1A1NPSR1FFAR1PTPN1 | |
| SCHEMBL100284 | 0.76 | FFAR1 (0.50) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL4779134 | 0.73 | PTPN1 (0.52) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL4773524 | 0.72 | PPARG (0.53) | PPARGALDH1A1NPSR1MAPTFFAR1 | |
| SCHEMBL8686495 | 0.71 | PPARG (0.44) | PPARGNPSR1MAPTFFAR1MPC2 | |
| SCHEMBL166570 | 0.71 | PPARG (0.74) | PPARGALDH1A1NPSR1MAPTFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |