Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4778666 | 0.82 | FFAR1 (0.48) | HDAC6HDAC1HDAC10ALDH1A1HPGD | |
| SCHEMBL5322829 | 0.81 | FFAR1 (0.45) | HDAC6HDAC1HDAC10ALDH1A1NPSR1 | |
| SCHEMBL4778234 | 0.74 | KDM4E (0.53) | MEN1KMT2AALDH1A1MAPK1HPGD | |
| SCHEMBL100284 | 0.74 | FFAR1 (0.50) | ALDH1A1HPGDNPSR1FFAR1PPARA | |
| SCHEMBL5324367 | 0.72 | PPARG (0.50) | ALDH1A1NPSR1LMNAFFAR1PPARA | |
| SCHEMBL9052053 | 0.68 | FFAR1 (0.50) | HDAC6HDAC1MEN1KMT2AALDH1A1 | |
| SCHEMBL4781441 | 0.67 | PTPN1 (0.52) | ALDH1A1NPSR1FFAR1PPARA | |
| SCHEMBL13846783 | 0.67 | HDAC1 (0.48) | HDAC6HDAC1HDAC10RAB9AALDH1A1 | |
| SCHEMBL4775009 | 0.66 | FFAR1 (0.45) | HDAC6HDAC1HDAC10ALDH1A1NPSR1 | |
| SCHEMBL11377635 | 0.66 | RAB9A (0.53) | HDAC6HDAC1HDAC10NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007119600-A9 | CARBAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2008-05-02 | — | — | WO | disclosed |
| WO-2007119600-A1 | CARBAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-10-25 | — | — | WO | disclosed |