Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 4/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.47 |
| ▸ | MMP3 | P08254 | 2/20 | 0.47 |
| ▸ | MMP7 | P09237 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316392 | 0.85 | SMN1; SMN2 (0.61) | GRIN2BMMP1MMP3MMP7MMP9 | |
| SCHEMBL5414884 | 0.85 | GPR119 (0.48) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL5449838 | 0.81 | CHRM4 (0.48) | GRIN2BMMP1MMP3MMP7MMP9 | |
| SCHEMBL6750128 | 0.77 | SMN1; SMN2 (0.53) | GRIN2BCHRM4PDE4BRAB9ASMN1; SMN2 | |
| SCHEMBL7503285 | 0.75 | SMN1; SMN2 (0.62) | GRIN2BCHRM4PDE4BRAB9ASMN1; SMN2 | |
| SCHEMBL13197107 | 0.75 | SMN1; SMN2 (0.65) | GRIN2BRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL14922380 | 0.75 | SMN1; SMN2 (0.56) | GRIN2BCHRM4PDE4BRAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7399417 | 0.75 | SMN1; SMN2 (0.57) | GRIN2BRAB9ASMN1; SMN2NPC1CYP2C19 | |
| SCHEMBL4035554 | 0.75 | SMN1; SMN2 (0.72) | GRIN2BCHRM4PDE4BRAB9ASMN1; SMN2 | |
| SCHEMBL4618960 | 0.75 | HRH3 (0.54) | PDE4BRAB9ASMN1; SMN2NPC1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | disclosed |