Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP7 | P09237 | 3/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP8 | P22894 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322836 | 0.85 | GRIN2B (0.48) | ALDH1A1HTTMMP1MMP3MMP7 | |
| SCHEMBL7871974 | 0.82 | ALDH1A1 (0.67) | GPR119ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL5463382 | 0.80 | ALDH1A1 (0.48) | GPR119ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL5947290 | 0.79 | ALDH1A1 (0.51) | GPR119ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL23411054 | 0.78 | ALDH1A1 (0.61) | GPR119ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL29891542 | 0.78 | ALDH1A1 (0.61) | GPR119ALDH1A1KDM4EHPGDHTT | |
| SCHEMBL5352679 | 0.77 | ALDH1A1 (0.50) | ALDH1A1KDM4E | |
| SCHEMBL23060497 | 0.75 | PDE4B (0.64) | GPR119ALDH1A1HPGDHTTSTS | |
| SCHEMBL8040438 | 0.74 | NAMPT (0.54) | GPR119ALDH1A1KDM4EHPGDTP53 | |
| SCHEMBL5458686 | 0.74 | ALDH1A1 (0.50) | GPR119ALDH1A1KDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007130712-A1 | SUBSTITUTED DIPIPERIDINE AS CCR2 ANTAGONISTS FOR THE TREATMENT OF INFLAMMATORY DISEASES | JANSSEN PHARMACEUTICA, NV (BE) | 2007-11-15 | — | — | WO | disclosed |