Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4894540 | 0.76 | HSD17B10 (0.53) | HSD17B10KDM4EHTTHPGDKMT2A | |
| SCHEMBL3440796 | 0.75 | ADRA2C (0.72) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| SCHEMBL29118505 | 0.74 | ADRA2C (0.53) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| SCHEMBL28229249 | 0.74 | ADRA2C (0.53) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| SCHEMBL2232108 | 0.74 | HSD17B10 (0.60) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| Bromide SCHEMBL30496129 | 0.73 | ADRA2C (0.70) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| SCHEMBL29049206 | 0.73 | HSD17B10 (0.55) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| Formic Acid SCHEMBL29049228 | 0.73 | HSD17B10 (0.55) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| Hydrochloric Acid SCHEMBL4373569 | 0.73 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHTTHPGD | |
| Iodide SCHEMBL29049215 | 0.73 | HSD17B10 (0.58) | ADRA2CHSD17B10KDM4EHTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |
| WO-2007134421-A1 | 2-VINYL INDOLES, PYRIDO AND AZEPINO INDOLE DERIVATIVES, 2-ALKYNYL INDOLES, 2-ALKYNYL BENZO[b]FURANS, THEIR PRECURSORS AND NOVEL PROCESSES FOR THE PREPARATION THEREOF | LAUTENS MARK (CA) | 2007-11-29 | — | — | WO | disclosed |