Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.39 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.39 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.39 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GAPDH | P04406 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320321 | 1.00 | POLB (0.43) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL5320327 | 1.00 | POLB (0.43) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL14436494 | 1.00 | POLB (0.43) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL19786805 | 0.90 | LMNA (0.51) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL13271933 | 0.90 | LMNA (0.51) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL14436577 | 0.87 | LMNA (0.46) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL18490625 | 0.85 | POLB (0.47) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL13211293 | 0.84 | POLB (0.47) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL2904043 | 0.84 | POLB (0.47) | POLBKMT2AMEN1USP2LMNA | |
| SCHEMBL14210620 | 0.84 | POLB (0.47) | POLBKMT2AMEN1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007093769-A1 | OLIGOSACCHARIDE BIOSYNTHESIS INHIBITORS | ISIS INNOVATION LIMITED (GB) | 2007-08-23 | — | — | WO | disclosed |