Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAT2A | P31153 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003068 | 0.83 | DYRK1A (0.53) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL30610433 | 0.76 | KDM4E (0.65) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1551352 | 0.76 | KDM4E (0.65) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL20522349 | 0.75 | KDM4E (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL30610423 | 0.75 | KDM4E (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18447982 | 0.75 | TDP1 (0.61) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL8793065 | 0.74 | PDE3B (0.46) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL14525860 | 0.74 | KDM4E (0.61) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL6700778 | 0.71 | KMT2A (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10429366 | 0.70 | ADORA1 (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858476-A1 | METHOD FOR INCREASING THE COLOR INTENSITY OF COLORATIONS ON KERATIN-CONTAINING SUBSTRATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-28 | — | — | EP | disclosed |
| WO-2006097158-A1 | METHOD FOR INCREASING THE COLOR INTENSITY OF COLORATIONS ON KERATIN-CONTAINING SUBSTRATES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-09-21 | — | — | WO | disclosed |