Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.47 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.43 |
| ▸ | NOS1 | P29475 | 1/20 | 0.43 |
| ▸ | NOS2 | P35228 | 1/20 | 0.43 |
| ▸ | MAT2A | P31153 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5322929 | 0.83 | DYRK1A (0.50) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL30622627 | 0.80 | DYRK1A (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18448865 | 0.80 | DYRK1A (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL10429366 | 0.79 | ADORA1 (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL30610433 | 0.79 | KDM4E (0.65) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL1551352 | 0.79 | KDM4E (0.65) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL20522349 | 0.78 | KDM4E (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL30610423 | 0.78 | KDM4E (0.54) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL18447982 | 0.78 | TDP1 (0.61) | DYRK1AKDM4EALDH1A1HPGDKMT2A | |
| SCHEMBL17555811 | 0.78 | KDM1A (0.45) | DYRK1AADORA1PTGS2ADORA2ANOS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 586 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3464247-B1 | NOVEL OXIDATION BASE DERIVED FROM 1-HEXYL-4,5- DIAMINOPYRAZOLE, COMPOSITION CONTAINING SAME AND USE THEREOF IN OXIDATION DYEING OF KERATIN FIBRES | OREAL (FR) | 2020-03-11 | — | — | EP | claimed |
| US-7189267-B2 | Oxyethylenated based hair pre-treatment anti-penetration composition and method using such a composition for limiting the penetration of dyes into the skin | L'OREAL (FR) | 2007-03-13 | — | — | US | claimed |
| US-7179301-B2 | Dyeing compositions for keratinous fibers containing paraphenylenediamine derivatives with pyrrolidinyl group | L'OREAL S.A. (FR) | 2007-02-20 | — | — | US | claimed |
| US-6723136-B2 | PRECURSOR OF AROMATIC RINGS HAVING HYDROXYL GROUPS ON ADJACENT CARBON ATOMS, AND OXIDATION BASE OF PARA OR ORTHO AROMATIC AMINES, AND A CATALYTIC SYSTEM OF SALTS AND OXIDES OF MANGANESE AND ZINC | L'OREAL (FR) | 2004-04-20 | — | — | US | claimed |
| EP-1367983-A1 | MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS | L'OREAL (FR) | 2003-12-10 | — | — | EP | claimed |
| US-20030172472-A1 | Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain | L'OREAL S.A. (FR) | 2003-09-18 | — | — | US | claimed |
| CN-1440267-A | Oxidation dyeing composition for keratinous fibres comprising amphoteric polymer with fatty chain | OREAL (FR) | 2003-09-03 | — | — | CN | claimed |
| EP-0994692-B1 | OXIDATION DYEING COMPOSITION FOR KERATINOUS FIBRES CONTAINING A 3-AMINOPYRIDINE AZO DERIVATIVE AND DYEING METHOD USING SAID COMPOSITION | OREAL (FR) | 2003-04-23 | — | — | EP | claimed |
| WO-2002069922-A1 | MICROCAPSULES WITH AQUEOUS CORE CONTAINING OXIDATION-REDUCTION ENZYMES AND THEIR USE IN OXIDATION DYEING COMPOSITIONS | L'OREAL (FR) | 2002-09-12 | — | — | WO | claimed |
| CN-1258214-A | Oxidation dyeing composition for keratinous fibres contg. 3-aminopyridine azo deriv. and dyeing method using said composition | OREAL (FR) | 2000-06-28 | — | — | CN | claimed |
| CN-118103023-A | Retarder composition and dye set comprising same | 莱雅公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118043027-A | Process for dyeing and/or lightening keratin fibres | 莱雅公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-112312883-B | Device for dispensing hair coloring products using dye compositions and oxidizing compositions comprising scleroglucan gum | 莱雅公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117715610-A | Composition for simultaneously bleaching and dyeing keratin fibers and method for using same | 莱雅公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-117715615-A | Composition comprising at least one oxidation dye, 1, 3-propanediol, at least one alkaline agent and at least one fatty substance | 莱雅公司 | 2024-03-15 | — | — | CN | disclosed |
| CN-1241137-A | Composition for the oxidation dyeing of keratin fibres and dyeing process using this composition | OREAL (FR) | 2000-01-12 | — | — | CN | disclosed |
| CN-1241138-A | Oxidation dyeing composition for keratin fibres and dyeing method using said composition | OREAL (FR) | 2000-01-12 | — | — | CN | disclosed |
| CN-1241135-A | Oxidation dyeing composition for keratin fibres | OREAL (FR) | 2000-01-12 | — | — | CN | disclosed |
| CN-1239422-A | Oxidation dyeing compsn. for keratin fibres and dyeing method of using same | OREAL (FR) | 1999-12-22 | — | — | CN | disclosed |
| CN-1236609-A | Oxidation dyeing composition of keration fibre and dyeing method using same | OREAL (FR) | 1999-12-01 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030172472-A1 | Oxidaton dyeing composition for keratinous fibres comprising an amphoteric polymer with fatty chain | KRT18, MB, MDN1 | DYRK1A 2799/4885KDM4E 2014/4885ALDH1A1 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.