Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5281260 | 0.77 | SMN1; SMN2 (0.64) | TRPV1 | |
| SCHEMBL5223625 | 0.75 | TRPV1 (0.38) | TRPV1 | |
| SCHEMBL5486486 | 0.74 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL5274596 | 0.70 | TRPV1 (0.52) | TRPV1 | |
| SCHEMBL3633978 | 0.70 | TRPV1 (0.51) | TRPV1 | |
| SCHEMBL303202 | 0.69 | TRPV1 (0.50) | TRPV1 | |
| SCHEMBL5354441 | 0.69 | TRPV1 (0.47) | TRPV1 | |
| SCHEMBL5345312 | 0.68 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL1379944 | 0.68 | — | — | |
| SCHEMBL5676140 | 0.68 | TRPV1 (0.49) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120012-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-10-25 | — | — | WO | disclosed |