Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.63 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 1/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.53 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23579792 | 0.86 | MAPT (0.78) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL14414255 | 0.83 | MAPT (0.62) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL5322398 | 0.83 | FLT3 (0.52) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL5321831 | 0.83 | ALDH1A1 (0.62) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL5322211 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL5320804 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL5321783 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL2368408 | 0.78 | LMNA (0.62) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL20665839 | 0.77 | SMN1; SMN2 (1.00) | ALDH1A1MAPTHPGDLMNAKDM4E | |
| SCHEMBL30033875 | 0.77 | SMN1; SMN2 (1.00) | ALDH1A1MAPTHPGDLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007102679-A1 | NOVEL THIENOPYRIMIDINE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | JE IL PHARMACEUTICAL CO., LTD. (KR) | 2007-09-13 | — | — | WO | disclosed |