Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1996410 | 0.78 | DPP4 (0.47) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL1997291 | 0.68 | DPP4 (0.44) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL1995841 | 0.62 | DPP4 (0.46) | DPP4DPP8CYP3A4 | |
| SCHEMBL6224473 | 0.62 | DPP4 (0.70) | DPP4DPP8DPP9CYP3A4CYP2C19 | |
| SCHEMBL2000319 | 0.62 | DPP4 (0.45) | DPP4DPP8 | |
| SCHEMBL6221533 | 0.61 | DPP4 (0.69) | DPP4DPP8DPP9CYP3A4 | |
| SCHEMBL464507 | 0.61 | AHR (0.64) | CYP3A4 | |
| SCHEMBL29624840 | 0.61 | AHR (0.64) | CYP3A4 | |
| SCHEMBL8277153 | 0.61 | DPP4 (0.64) | DPP4DPP8CYP3A4 | |
| SCHEMBL3149261 | 0.61 | DPP4 (1.00) | DPP4DPP8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007112347-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-04 | — | — | WO | claimed |
| WO-2007112347-A1 | DIPEPTIDYL PEPTIDASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-10-04 | — | — | WO | disclosed |