Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327068 | 1.00 | KMT2A (0.44) | KMT2ASMN1; SMN2KDM4EGLAALDH1A1 | |
| SCHEMBL5450968 | 0.78 | TSHR (0.54) | KMT2ASMN1; SMN2KDM4EHTTMEN1 | |
| SCHEMBL5323319 | 0.78 | HTT (0.38) | KMT2ASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL5323320 | 0.76 | MAPT (0.50) | KMT2ASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL5329373 | 0.76 | MAPT (0.50) | KMT2ASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL20898212 | 0.76 | MAPT (0.50) | KMT2ASMN1; SMN2KDM4EALDH1A1GAA | |
| SCHEMBL20526919 | 0.76 | KMT2A (0.43) | KMT2ASMN1; SMN2ALDH1A1HTTMEN1 | |
| SCHEMBL8180147 | 0.74 | NPC1 (0.47) | KMT2ASMN1; SMN2ALDH1A1HSD17B10HTT | |
| SCHEMBL5325359 | 0.74 | KDM4E (0.41) | KDM4EGLAALDH1A1GAAHPGD | |
| SCHEMBL5323891 | 0.74 | KDM4E (0.41) | KDM4EGLAALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |