Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8180147 | 0.79 | NPC1 (0.47) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL5327068 | 0.78 | KMT2A (0.44) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL5323314 | 0.78 | KMT2A (0.44) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL5323321 | 0.77 | ALDH1A1 (0.50) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL5329375 | 0.77 | ALDH1A1 (0.50) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL27626448 | 0.73 | RAB9A (0.38) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL10702555 | 0.71 | ALDH1A1 (0.50) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL16178878 | 0.71 | ALDH1A1 (0.48) | HTTNPC1L3MBTL1RAB9AMAPT | |
| SCHEMBL5323899 | 0.71 | AAK1 (0.37) | — | |
| SCHEMBL5450968 | 0.71 | TSHR (0.54) | HTTL3MBTL1KMT2ASMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |