Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 10/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.43 |
| ▸ | FABP2 | P12104 | 1/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.41 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325861 | 0.86 | PPARA (0.56) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL2668319 | 0.79 | PPARA (0.54) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5324713 | 0.76 | PPARA (0.61) | PPARAPPARGPPARD | |
| SCHEMBL787522 | 0.76 | PPARA (0.67) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5324710 | 0.75 | PPARA (0.47) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL17469614 | 0.75 | APP (0.67) | FFAR1CYP3A4MAPTALDH1A1KCNH2 | |
| SCHEMBL9611202 | 0.73 | FFAR1 (0.59) | FFAR1CYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5331645 | 0.72 | FFAR1 (0.50) | FFAR1CYP3A4MAPTMAP4K4 | |
| SCHEMBL27654984 | 0.72 | PPARG (0.70) | PPARAPPARGPPARD | |
| SCHEMBL29462452 | 0.72 | MAPT (0.62) | FFAR1CYP2C19MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |