Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 8/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FABP2 | P12104 | 1/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5327149 | 0.85 | PPARA (0.48) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL2668319 | 0.78 | PPARA (0.54) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL10714994 | 0.77 | PPARA (0.61) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL3482673 | 0.76 | CYP3A4 (0.48) | MEN1KMT2ACYP3A4CYP2D6MAPT | |
| SCHEMBL7002896 | 0.75 | ALDH1A1 (0.53) | CYP2C19CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8413205 | 0.75 | PPARA (0.59) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL12777729 | 0.75 | PPARA (0.68) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5323680 | 0.75 | FFAR1 (0.51) | PPARACYP2C19MEN1KMT2ACYP1A2 | |
| SCHEMBL5324713 | 0.75 | PPARA (0.61) | PPARAADRB3PPARGPPARD | |
| SCHEMBL787522 | 0.75 | PPARA (0.67) | PPARACYP2C19MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007141423-A1 | PPAR ENHANCING DERIVATIVES, METHOD FOR PREPARING SAME AND THERAPEUTIC USE THEREOF | NEGMA-LERADS (FR) | 2007-12-13 | — | — | WO | disclosed |