Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.46 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.46 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | GRM6 | O15303 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | PRKDC | P78527 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2839282 | 0.94 | MAPT (0.46) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL2773208 | 0.88 | MAPT (0.53) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL14993728 | 0.87 | TDP1 (0.42) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5291433 | 0.83 | MAPT (0.54) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5027796 | 0.83 | EGFR (0.47) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL16664635 | 0.83 | MAPT (0.45) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11251378 | 0.81 | ALDH1A1 (0.55) | MAPTALOX15CYP1A2TDP1POLB | |
| SCHEMBL17429736 | 0.81 | VCAM1 (0.45) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL19295308 | 0.81 | ALDH1A1 (0.45) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL11163249 | 0.80 | ALDH1A1 (0.47) | MAPTGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |