Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MPI | P34949 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10454920 | 0.87 | HRH3 (0.72) | HRH3CYP2C9ALOX15HSD17B10KMT2A | |
| SCHEMBL5323114 | 0.81 | KMT2A (0.49) | HRH3CYP2C9ALOX15HSD17B10KMT2A | |
| SCHEMBL23964430 | 0.81 | MAPT (0.49) | HRH3CYP2C9ALOX15HSD17B10KMT2A | |
| SCHEMBL23964432 | 0.81 | MEN1 (0.49) | HRH3CYP2C9ALOX15HSD17B10KMT2A | |
| SCHEMBL23926340 | 0.81 | ERN1 (0.46) | HRH3CYP2C9ALOX15HSD17B10KMT2A | |
| SCHEMBL2799254 | 0.81 | HRH3 (0.54) | HRH3LMNASIGMAR1HTR2AHTR2C | |
| SCHEMBL23926333 | 0.77 | SIGMAR1 (0.61) | HRH3KMT2AMEN1KDM4EHTT | |
| SCHEMBL738862 | 0.77 | SIGMAR1 (0.47) | HRH3L3MBTL1SIGMAR1POLBCYP2A13 | |
| SCHEMBL24127975 | 0.76 | POLB (0.51) | CYP2C9ALOX15HSD17B10KMT2AMEN1 | |
| SCHEMBL4425954 | 0.75 | SIGMAR1 (0.53) | HRH3KMT2AMEN1L3MBTL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114672-A1 | AGENT FOR THE PREVENTION AND TREATMENT OF METABOLIC BONE DISEASE BY ENHANCING OSTEOPROTEGERIN SECRETION | OSCOTEC INC. (KR) | 2007-10-11 | — | — | WO | disclosed |