Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CTSH | P09668 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8526731 | 0.90 | CTSL (0.57) | CTSKCTSL | |
| SCHEMBL9143156 | 0.88 | CTRB1 (0.61) | CTSCNPC1RAB9ACTRB1CYP3A4 | |
| SCHEMBL27602044 | 0.88 | CTRB1 (0.61) | CTSCNPC1RAB9ACTRB1CYP3A4 | |
| SCHEMBL7316163 | 0.88 | CTRB1 (0.61) | CTSCNPC1RAB9ACTRB1CYP3A4 | |
| SCHEMBL7316156 | 0.88 | CTRB1 (0.61) | CTSCNPC1RAB9ACTRB1CYP3A4 | |
| SCHEMBL27788518 | 0.88 | CTSC (0.57) | CTSCNPC1RAB9ACTRB1CYP3A4 | |
| SCHEMBL9389290 | 0.84 | CTSC (0.76) | CTSCCYP3A4CYP1A2CTSHCYP2D6 | |
| SCHEMBL1691349 | 0.84 | CTSC (0.76) | CTSCCYP3A4CYP1A2CTSHCYP2D6 | |
| SCHEMBL583122 | 0.84 | CTSC (0.76) | CTSCCYP3A4CYP1A2CTSHCYP2D6 | |
| SCHEMBL583121 | 0.84 | CTSC (0.76) | CTSCCYP3A4CYP1A2CTSHCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967062-A | The analogs of novel C C 1065 and its conjugate | 辛塔佳股份有限公司 | 2017-07-21 | — | — | CN | disclosed |
| CN-101415679-A | Water-soluble CC-1065 analogs and conjugates thereof | SINTAGAR B V (NL) | 2009-04-22 | — | — | CN | disclosed |
| WO-2007112348-A2 | PRODRUG COMPOSITION | TSRL, INC. (US) | 2007-10-04 | — | — | WO | disclosed |
| WO-1994018230-A1 | INHIBITION OF HIV REPLICATION BY PEPTIDE-COPPER COMPLEXES | PROCYTE CORPORATION (US) | 1994-08-18 | — | — | WO | disclosed |