Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CD69 | Q07108 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324774 | 0.83 | TSHR (0.48) | PTGDR2CYP2C19TSHRALDH1A1GLA | |
| SCHEMBL4576631 | 0.82 | PKM (0.65) | PTGDR2PKMALOX15TSHRHSD17B10 | |
| SCHEMBL29367635 | 0.81 | PTGDR2 (0.49) | PTGDR2PKMCYP2C19ALOX15TSHR | |
| SCHEMBL31335940 | 0.77 | KDM4E (0.32) | PTGDR2ALDH1A1 | |
| SCHEMBL29368471 | 0.76 | PKM (0.47) | PTGDR2PKMCYP2C19ALOX15TSHR | |
| SCHEMBL3923991 | 0.73 | SMN1; SMN2 (0.57) | PTGDR2ALOX15TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL5320268 | 0.73 | CYP2C19 (0.68) | PTGDR2PKMCYP2C19ALOX15TSHR | |
| SCHEMBL17896565 | 0.73 | SMN1; SMN2 (0.57) | PTGDR2ALOX15TSHRHSD17B10SMN1; SMN2 | |
| SCHEMBL12478128 | 0.73 | PTGDR2 (1.00) | PTGDR2PKMCYP2C19ALOX15TSHR | |
| SCHEMBL3384185 | 0.71 | PKM (0.46) | PTGDR2PKMCYP2C19TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007120012-A1 | NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST; AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | AMOREPACIFIC CORPORATION (KR) | 2007-10-25 | — | — | WO | disclosed |