Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 2/20 | 0.57 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.57 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.57 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20618432 | 0.87 | GNAI3 (0.44) | GNAI3GNAO1GNAI1SPHK1SIGMAR1 | |
| SCHEMBL21584004 | 0.87 | GNAI3 (0.44) | GNAI3GNAO1GNAI1SPHK1SIGMAR1 | |
| SCHEMBL2803853 | 0.86 | GNAI3 (0.50) | GNAI3GNAO1GNAI1SPHK1HRH2 | |
| Hydrochloric Acid SCHEMBL2300838 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1HRH2 | |
| Hydrochloric Acid SCHEMBL2293794 | 0.84 | GNAI3 (0.53) | GNAI3GNAO1GNAI1SPHK1HRH2 | |
| SCHEMBL3966764 | 0.84 | GNAI3 (0.59) | GNAI3GNAO1GNAI1SPHK1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL3668361 | 0.82 | GNAI3 (0.62) | GNAI3GNAO1GNAI1SPHK1SIGMAR1 | |
| SCHEMBL23448772 | 0.79 | GNAI3 (0.59) | GNAI3GNAO1GNAI1SPHK1HRH2 | |
| SCHEMBL3973508 | 0.78 | ALOX15 (0.60) | GNAI3GNAO1GNAI1SPHK1SIGMAR1 | |
| SCHEMBL6889855 | 0.77 | CARM1 (0.52) | SIGMAR1HRH3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116744920-A | Heteroaryl piperidine derivative, and pharmaceutical composition and application thereof | 贝达药业股份有限公司 | 2023-09-12 | — | — | CN | claimed |
| WO-2022166983-A1 | HETEROARYLOPIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 贝达药业股份有限公司 | 2022-08-11 | — | — | WO | claimed |
| WO-2007134127-A2 | AGENTS FOR IMAGING APOPTOSIS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2007-11-22 | — | — | WO | claimed |
| CN-116744920-A | Heteroaryl piperidine derivative, and pharmaceutical composition and application thereof | 贝达药业股份有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2022166983-A1 | HETEROARYLOPIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 贝达药业股份有限公司 | 2022-08-11 | — | — | WO | disclosed |
| WO-2022166983-A1 | HETEROARYLOPIPERIDINE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 贝达药业股份有限公司 | 2022-08-11 | — | — | WO | disclosed |