Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPD | P32754 | 7/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15623075 | 0.87 | KMT2A (0.46) | HPGDPOLBALDH1A1KMT2APTK2B | |
| SCHEMBL23352311 | 0.86 | NPC1 (0.53) | HPGDPOLBALDH1A1KMT2ANPC1 | |
| SCHEMBL7828058 | 0.84 | GLA (0.50) | ALDH1A1KMT2ATSHRHPD | |
| SCHEMBL3931562 | 0.83 | MEN1 (0.55) | KMT2AAKR1C3AKR1C2AKR1C1 | |
| SCHEMBL25435457 | 0.83 | SMN1; SMN2 (0.50) | HPGDPOLBALDH1A1KMT2ANPC1 | |
| SCHEMBL29740471 | 0.83 | PKM (0.59) | HPGDPOLBALDH1A1KMT2ATSHR | |
| SCHEMBL104452 | 0.83 | PKM (0.59) | HPGDPOLBALDH1A1KMT2ATSHR | |
| SCHEMBL3372774 | 0.81 | NPC1 (0.60) | HPGDALDH1A1KMT2ATSHRNPC1 | |
| SCHEMBL837892 | 0.81 | ALDH1A1 (0.55) | HPGDPOLBALDH1A1KMT2ATSHR | |
| SCHEMBL29158279 | 0.81 | POLB (0.42) | HPGDPOLBALDH1A1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650196-A1 | PROCESS FOR PRODUCING 6,7-BIS(2-METHOXYETHOXY)-QUINAZOLIN-4-ONE | Ube Industries, Ltd. (JP) | 2006-04-26 | — | — | EP | claimed |
| CN-113166156-B | Tyrosine kinase inhibitors, compositions and methods | 贝达药业股份有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-3891152-A1 | TYROSINE KINASE INHIBITORS, COMPOSITIONS AND METHODS THERE OF | Betta Pharmaceuticals Co., Ltd (CN) | 2021-10-13 | — | — | EP | disclosed |
| CN-113166156-A | Tyrosine kinase inhibitors, compositions and methods thereof | 贝达药业股份有限公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020114499-A1 | TYROSINE KINASE INHIBITORS, COMPOSITIONS AND METHODS THERE OF | BETTA PHARMACEUTICALS CO., LTD (CN) | 2020-06-11 | — | — | WO | disclosed |
| WO-2007138613-A2 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4-YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) | 2007-12-06 | — | — | WO | disclosed |
| WO-2007138612-A2 | A PROCESS FOR SYNTHESIS OF [6,7-BIS-(2-METHOXYETHOXY)-QUINAZOLIN-4- YL]-(3-ETHYNYLPHENYL)AMINE HYDROCHLORIDE | VITTAL MALLYA SCIENTIFIC RESEARCH FOUNDATION (IN) | 2007-12-06 | — | — | WO | disclosed |
| US-20060276647-A1 | Process for producing 6, 7-bis (2-methoxyethoxy)-quinazolin-4-one | UBE INDUSTRIES, LTD (JP) | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276647-A1 | Process for producing 6, 7-bis (2-methoxyethoxy)-quinazolin-4-one | CPS1, CYP3A4, RPS27A | HPGD 1178/4885POLB 430/4885ALDH1A1 1913/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.