Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 9/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL584155 | 0.91 | HPGD (0.44) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL6037295 | 0.88 | HPGD (0.48) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL10436328 | 0.85 | FTO (0.44) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL3748733 | 0.79 | HPGD (0.49) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL314241 | 0.77 | ALB (0.51) | HPGDALDH1A1FTOMEN1MAPT | |
| SCHEMBL5872498 | 0.77 | FTO (0.50) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL6530338 | 0.77 | ALB (0.38) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL6531298 | 0.76 | FTO (0.49) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL375100 | 0.76 | FTO (0.49) | HPGDALDH1A1CYP2C9ALOX15ALOX12 | |
| SCHEMBL19207355 | 0.76 | HPGD (0.54) | HPGDALDH1A1CYP2C9ALOX15ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070293451-A1 | Regulation ao ApoB by Hsp110 proteins and related compositions and methods | UNIVERSITY OF PITTSBURGH (US) | 2007-12-20 | — | — | US | claimed |
| WO-2007130403-A2 | REGULATION OF ApoB BY Hspl 10 PROTEINS AND RELATED COMPOSITIONS AND METHODS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2007-11-15 | — | — | WO | claimed |
| US-20070293451-A1 | Regulation ao ApoB by Hsp110 proteins and related compositions and methods | UNIVERSITY OF PITTSBURGH (US) | 2007-12-20 | — | — | US | disclosed |
| WO-2007130403-A2 | REGULATION OF ApoB BY Hspl 10 PROTEINS AND RELATED COMPOSITIONS AND METHODS | UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2007-11-15 | — | — | WO | disclosed |