Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.74 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.54 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 2/20 | 0.52 |
| ▸ | THRA | P10827 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9272097 | 0.87 | FFAR1 (0.64) | FFAR1CHRM1NR3C1TDP1MRGPRX4 | |
| SCHEMBL12667945 | 0.85 | FFAR1 (1.00) | FFAR1CHRM1TDP1MRGPRX4TTR | |
| SCHEMBL13742641 | 0.82 | FFAR1 (0.56) | FFAR1CHRM1NR3C1PTGDR2THRA | |
| SCHEMBL13742516 | 0.82 | PNLIP (0.59) | FFAR1NR3C1PTGDR2 | |
| SCHEMBL6441891 | 0.82 | SRD5A2 (0.62) | FFAR1NR3C1PTGDR2THRATHRB | |
| SCHEMBL28275130 | 0.80 | MRGPRX4 (0.70) | FFAR1MRGPRX4TTR | |
| SCHEMBL23120336 | 0.79 | FFAR1 (0.52) | FFAR1NR3C1PTGDRPTGDR2THRA | |
| SCHEMBL8332044 | 0.79 | FFAR1 (0.71) | FFAR1CHRM1TDP1MRGPRX4PTGDR2 | |
| SCHEMBL13742653 | 0.79 | PNLIP (0.67) | FFAR1PTGDRPTGDR2 | |
| SCHEMBL11574819 | 0.78 | CHRM1 (0.58) | FFAR1CHRM1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442655-B1 | Benzisoxazole derivatives | ZENECA LTD (GB) | 1996-01-17 | — | — | EP | disclosed |
| US-5176737-A | BENZISOXAZOLE COMPOUNDS USEFUL AS HERBICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-01-05 | — | — | US | disclosed |
| EP-0442655-A2 | Benzisoxazole derivatives | ZENECA LIMITED (GB) | 1991-08-21 | — | — | EP | disclosed |
| EP-0057047-B1 | PROCESS FOR THE PREPARATION OF 2-(2,4-DICHLOROPHENOXY) PHENYLACETIC ACID | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1984-08-08 | — | — | EP | disclosed |
| US-4404396-A | Process for the preparation of 2-(2,4-dichlorophenoxy)-phenylacetic acid | RECKITT & COLMAN PRODUCTS LIMITED (GB) | 1983-09-13 | — | — | US | disclosed |
| EP-0057047-A1 | Process for the preparation of 2-(2,4-dichlorophenoxy) phenylacetic acid | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1982-08-04 | — | — | EP | disclosed |