Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.31 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.31 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.31 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.31 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.31 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.31 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.31 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.31 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.31 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321292 | 0.84 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL3138226 | 0.82 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL6067443 | 0.81 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL9067237 | 0.79 | ZDHHC20 (0.53) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL448048 | 0.79 | ALDH1A1 (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL21734442 | 0.77 | ALDH1A1 (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28017327 | 0.74 | ZDHHC20 (0.40) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL21734385 | 0.74 | ALDH1A1 (0.41) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL2900184 | 0.74 | TSHR (0.36) | TSHR | |
| SCHEMBL8503644 | 0.74 | EPHX1 (0.39) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729224-A | Michael addition hardening hybrid system for chemical fixation technology | 费希尔厂有限责任两合公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114729253-A | Michael addition hardening synthetic resin for chemical fixing technology | 费希尔厂有限责任两合公司 | 2022-07-08 | — | — | CN | claimed |
| CN-114729224-A | Michael addition hardening hybrid system for chemical fixation technology | 费希尔厂有限责任两合公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114729253-A | Michael addition hardening synthetic resin for chemical fixing technology | 费希尔厂有限责任两合公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2007122121-A2 | UV-CROSSLINKABLE POLYSILOXANES | WACKER CHEMIE AG (DE) | 2007-11-01 | — | — | WO | disclosed |