Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321989 | 0.91 | DRD2 (0.48) | DRD2ADRA1AKDM4ERECQLLRRK2 | |
| SCHEMBL5323016 | 0.89 | DRD2 (0.46) | DRD2ADRA1AHTTKMT2AALDH1A1 | |
| SCHEMBL5324511 | 0.88 | DRD2 (0.49) | DRD2ADRA1AKDM4ERECQLNPSR1 | |
| SCHEMBL5320284 | 0.85 | DRD2 (0.46) | DRD2ADRA1AKDM4ERECQLHTT | |
| SCHEMBL5324853 | 0.83 | DRD2 (0.67) | DRD2ADRA1A | |
| SCHEMBL5327258 | 0.83 | DRD2 (0.46) | DRD2ADRA1AKDM4ERECQLHTT | |
| SCHEMBL5320467 | 0.83 | DRD2 (0.44) | DRD2ADRA1AKDM4ERECQLHTT | |
| SCHEMBL5348013 | 0.83 | DRD2 (0.59) | DRD2ADRA1A | |
| SCHEMBL5324721 | 0.82 | DRD2 (0.56) | DRD2ADRA1AKMT2AALDH1A1MEN1 | |
| SCHEMBL5322183 | 0.81 | DRD2 (0.49) | DRD2ADRA1AKDM4ERECQLNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114902-A2 | ALKYLTHIOBENZYLPIPERIDINE COMPOUNDS | H.LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | disclosed |