Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324511 | 0.88 | DRD2 (0.49) | DRD2ADRA1AKDM4ERECQL | |
| SCHEMBL5320284 | 0.87 | DRD2 (0.46) | DRD2ADRA1AKDM4ERECQLALDH1A1 | |
| SCHEMBL5323016 | 0.87 | DRD2 (0.46) | DRD2ADRA1AALDH1A1HTT | |
| SCHEMBL5327258 | 0.85 | DRD2 (0.46) | DRD2ADRA1AKDM4ERECQLALDH1A1 | |
| SCHEMBL5320472 | 0.85 | DRD2 (0.51) | DRD2ADRA1A | |
| SCHEMBL5321989 | 0.84 | DRD2 (0.48) | DRD2ADRA1AKDM4ERECQLALDH1A1 | |
| SCHEMBL5324720 | 0.83 | DRD2 (0.47) | DRD2ADRA1AKDM4ERECQLALDH1A1 | |
| SCHEMBL5322375 | 0.78 | DRD2 (0.41) | DRD2ADRA1AALDH1A1 | |
| SCHEMBL5322183 | 0.78 | DRD2 (0.49) | DRD2ADRA1AKDM4ERECQL | |
| SCHEMBL5348013 | 0.78 | DRD2 (0.59) | DRD2ADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007114916-A2 | ARYLBENZYLPIPERIDINE COMPOUNDS | H. LUNDBECK A/S (DK) | 2007-10-11 | — | — | WO | claimed |