Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.77 |
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.67 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.67 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA4 | P22748 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | FABP2 | P12104 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324956 | 1.00 | LMNA (0.77) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL13704166 | 0.87 | LMNA (1.00) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5350109 | 0.86 | LMNA (0.84) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5350115 | 0.86 | LMNA (0.84) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5325984 | 0.85 | LMNA (0.82) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5325980 | 0.85 | LMNA (0.82) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5347324 | 0.81 | LMNA (0.79) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL5347330 | 0.81 | LMNA (0.79) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL28669346 | 0.81 | LMNA (0.86) | LMNASMN1; SMN2MAPTMEN1KMT2A | |
| SCHEMBL23070444 | 0.80 | AKR1C3 (1.00) | LMNAMAPTMEN1KMT2AAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095383-A2 | PRODRUGS | MYRIAD GENETICS, INC. (US) | 2007-08-23 | — | — | WO | disclosed |