Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 1/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.40 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324981 | 1.00 | STS (0.47) | STSFKBP1AHRH3ANO1JAK3 | |
| SCHEMBL5324977 | 1.00 | STS (0.47) | STSFKBP1AHRH3ANO1JAK3 | |
| SCHEMBL5332291 | 0.83 | GRM2 (0.48) | FKBP1AHRH3GRM2TP53 | |
| SCHEMBL31071546 | 0.82 | STS (0.53) | STSSMN1; SMN2POLBTP53 | |
| SCHEMBL29120051 | 0.80 | USP30 (0.51) | STSSMN1; SMN2POLBTP53 | |
| SCHEMBL8225431 | 0.79 | USP30 (0.45) | JAK3 | |
| SCHEMBL29913093 | 0.77 | JAK3 (0.41) | STSANO1JAK3 | |
| SCHEMBL712166 | 0.77 | SMN1; SMN2 (0.47) | STSANO1JAK3SMN1; SMN2TP53 | |
| SCHEMBL2616222 | 0.77 | FKBP1A (0.65) | STSFKBP1ASMN1; SMN2 | |
| SCHEMBL13481738 | 0.76 | STS (0.42) | STSHRH3GRM2POLBHDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |