Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | RXRB | P28702 | 1/20 | 0.45 |
| ▸ | RXRG | P48443 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324970 | 0.83 | STS (0.47) | GRM2FKBP1ATP53HRH3 | |
| SCHEMBL5324977 | 0.83 | STS (0.47) | GRM2FKBP1ATP53HRH3 | |
| SCHEMBL5324981 | 0.83 | STS (0.47) | GRM2FKBP1ATP53HRH3 | |
| SCHEMBL5322226 | 0.75 | TAAR1 (0.47) | GRM2KDM4EALDH1A1HRH3 | |
| SCHEMBL5322223 | 0.75 | TAAR1 (0.47) | GRM2KDM4EALDH1A1HRH3 | |
| SCHEMBL5322220 | 0.75 | TAAR1 (0.47) | GRM2KDM4EALDH1A1HRH3 | |
| SCHEMBL27158547 | 0.73 | HDAC4 (0.37) | — | |
| SCHEMBL6274777 | 0.73 | GRM2 (0.45) | GRM2FKBP1ARXRARXRBRXRG | |
| SCHEMBL27158544 | 0.73 | HDAC4 (0.37) | — | |
| SCHEMBL23149400 | 0.72 | MGLL (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135529-A2 | AZABENZIMIDAZOLYL COMPOUNDS AS MGLUR2 POTENTIATORS | PFIZER PRODUCTS INC. (US) | 2007-11-29 | — | — | WO | disclosed |