SCHEMBL532507

SCHEMBL532507

COc1cccc(-c2cccc(-n3c4ccc(-c5ccccc5)cc4c4cc(-c5ccccc5)ccc43)c2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 2/20 0.46
KDR P35968 1/20 0.45
MAOB P27338 2/20 0.44
KDM4E B2RXH2 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
ABL1 P00519 1/20 0.44
ABCB1 P08183 1/20 0.44
BCR P11274 1/20 0.44
BRD4 O60885 1/20 0.43
MEN1 O00255 1/20 0.43
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C9 P11712 1/20 0.43
BRAF P15056 1/20 0.43
TSHR P16473 1/20 0.43
MAPK1 P28482 1/20 0.43
CYP2C19 P33261 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532536 0.97 TSPO (0.47) TSPOKDRMAOBKDM4ESMN1; SMN2
SCHEMBL27864514 0.93 TSPO (0.53) TSPOKDRKDM4ESMN1; SMN2MEN1
SCHEMBL23186647 0.90 TSPO (0.50) TSPOKDM4ESMN1; SMN2MEN1CYP1A2
SCHEMBL15625370 0.88 KDM4E (0.54) TSPOKDM4ESMN1; SMN2MEN1KMT2A
SCHEMBL8739888 0.86 ATM (0.47) TSPOKDM4ESMN1; SMN2USP2CYP1A2
SCHEMBL20633476 0.86 ATM (0.47) TSPOKDM4ESMN1; SMN2USP2CYP1A2
SCHEMBL14660171 0.85 ABL1 (0.50) TSPOMAOBKDM4EABL1ABCB1
SCHEMBL14903461 0.85 KDM4E (0.58) KDRKDM4ESMN1; SMN2MEN1MAPK1
SCHEMBL3365404 0.85 KDR (0.56) TSPOKDRKDM4ESMN1; SMN2ABL1
SCHEMBL20633125 0.85 ATM (0.50) TSPOKDM4ESMN1; SMN2MEN1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416392-B1 Light emitting device and display unit RICOH CO LTD (JP) 2016-05-25 EP disclosed
US-9263682-B2 Light emitting device and display unit RICOH COMPANY, LTD. (JP) 2016-02-16 US disclosed
US-9206202-B2 Carbazole derivative and semiconductor nanocrystal RICOH COMPANY, LTD. (JP) 2015-12-08 US disclosed
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL RICOH COMPANY, LTD. (JP) 2013-01-31 US disclosed
US-20120032115-A1 LIGHT EMITTING DEVICE AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2416392-A2 Light emitting device and display unit Ricoh Company, Ltd. (JP) 2012-02-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130026426-A1 CARBAZOLE DERIVATIVE AND SEMICONDUCTOR NANOCRYSTAL NAT1, AHR, ARSA TSPO 2744/4885KDR 3620/4885MAOB 1522/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.