SCHEMBL532536

SCHEMBL532536

COc1cccc(-n2c3ccc(-c4ccccc4)cc3c3cc(-c4ccccc4)ccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 3/20 0.47
KDR P35968 1/20 0.47
KDM4E B2RXH2 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
MAPT P10636 2/20 0.45
HTT P42858 2/20 0.45
MAOB P27338 1/20 0.43
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43
HSD17B10 Q99714 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
NTRK1 P04629 1/20 0.43
IGF1R P08069 1/20 0.43
FGFR1 P11362 1/20 0.43
NTRK2 Q16620 1/20 0.43
NOTUM Q6P988 1/20 0.43
ABL1 P00519 1/20 0.42
ABCB1 P08183 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL532507 0.97 TSPO (0.46) TSPOKDRKDM4ESMN1; SMN2MAPT
SCHEMBL27864514 0.96 TSPO (0.53) TSPOKDRKDM4ESMN1; SMN2MAPT
SCHEMBL15625370 0.91 KDM4E (0.54) TSPOKDM4ESMN1; SMN2MAPTHTT
SCHEMBL23186647 0.90 TSPO (0.50) TSPOKDM4ESMN1; SMN2MAPTHTT
SCHEMBL14903461 0.88 KDM4E (0.58) KDRKDM4ESMN1; SMN2MAPTHTT
SCHEMBL3365404 0.88 KDR (0.56) TSPOKDRKDM4ESMN1; SMN2MAPT
SCHEMBL16805780 0.87 ABCG2 (0.48) TSPOKDM4ESMN1; SMN2MAPTHTT
SCHEMBL532374 0.86 OXTR (0.55) TSPOKDRKDM4ESMN1; SMN2MAPT
SCHEMBL17694116 0.86 KDM4E (0.56) TSPOKDRKDM4ESMN1; SMN2MAPT
SCHEMBL20633476 0.85 ATM (0.47) TSPOKDM4ESMN1; SMN2HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416392-B1 Light emitting device and display unit RICOH CO LTD (JP) 2016-05-25 EP disclosed
US-9263682-B2 Light emitting device and display unit RICOH COMPANY, LTD. (JP) 2016-02-16 US disclosed
US-20120032115-A1 LIGHT EMITTING DEVICE AND DISPLAY UNIT RICOH COMPANY, LTD. (JP) 2012-02-09 US disclosed
EP-2416392-A2 Light emitting device and display unit Ricoh Company, Ltd. (JP) 2012-02-08 EP disclosed