Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 3/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | SI | P14410 | 1/20 | 0.43 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12431888 | 0.78 | HTR1A (0.50) | KMT2AMEN1TDP1BCHEHTR1A | |
| SCHEMBL10925538 | 0.78 | HTR1A (0.50) | KMT2AMEN1TDP1BCHEHTR1A | |
| SCHEMBL27998563 | 0.78 | MAOB (0.59) | KMT2AMEN1BCHEHTR1AADRA1D | |
| SCHEMBL5306047 | 0.77 | G6PD (0.57) | KMT2AMEN1TDP1BCHEHTR1A | |
| SCHEMBL5308499 | 0.77 | TAAR1 (0.51) | KMT2AMEN1TDP1 | |
| SCHEMBL19738039 | 0.77 | KMT2A (0.50) | KMT2AMEN1TDP1BCHEHTR1A | |
| SCHEMBL5308504 | 0.77 | TAAR1 (0.51) | KMT2AMEN1TDP1 | |
| SCHEMBL5234365 | 0.76 | HTR1A (0.49) | KMT2AMEN1TDP1BCHEHTR1A | |
| SCHEMBL5237170 | 0.76 | APP (0.56) | KMT2AMEN1TDP1BCHEHTR1A | |
| SCHEMBL8862695 | 0.76 | HTR1A (0.49) | KMT2AMEN1TDP1BCHEHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007016190-A2 | ANTIPARKINSONIAN ACTION OF PHENYLISOPROPYLAMINES | DUKE UNIVERSITY (US) | 2007-02-08 | — | — | WO | disclosed |