Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | SCD | O00767 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5328060 | 0.85 | PPARA (0.58) | PPARAPPARDCHRM4GAAMAPT | |
| SCHEMBL244641 | 0.79 | SCD (0.58) | PPARACHRM4MAPTSCDSMN1; SMN2 | |
| SCHEMBL12464766 | 0.79 | PPARA (0.69) | PPARAPPARDCHRM4GAAMAPT | |
| SCHEMBL13541868 | 0.79 | PPARA (0.69) | PPARAPPARDMAPTSCD | |
| SCHEMBL3042709 | 0.78 | CHRM4 (0.57) | PPARACHRM4MAPTSCDSMN1; SMN2 | |
| SCHEMBL3454547 | 0.78 | SCD (0.57) | PPARACHRM4MAPTSCDSMN1; SMN2 | |
| SCHEMBL3455092 | 0.78 | PPARD (0.56) | PPARAPPARDCHRM4GAAMAPT | |
| SCHEMBL3575995 | 0.78 | CHRM4 (0.61) | PPARAPPARDCHRM4GAAMAPT | |
| SCHEMBL18320904 | 0.78 | SMN1; SMN2 (0.55) | PPARAGAAMAPTSMN1; SMN2KLKB1 | |
| SCHEMBL4285011 | 0.78 | RAB9A (0.71) | GAAMAPTSMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007138110-A2 | COMPOUNDS THAT INTERACT WITH ION CHANNELS, IN PARTICULAR WITH ION CHANNELS FROM THE KV FAMILY | DEVGEN N.V. (BE) | 2007-12-06 | — | — | WO | claimed |