Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 18/20 | 0.53 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5414724 | 0.93 | HTR6 (0.52) | HTR6CYP3A4 | |
| SCHEMBL5332557 | 0.87 | HTR6 (0.46) | HTR6CYP3A4 | |
| SCHEMBL5326098 | 0.86 | HTR6 (0.57) | HTR6CYP3A4 | |
| SCHEMBL5331226 | 0.86 | HTR6 (0.57) | HTR6 | |
| SCHEMBL5414225 | 0.82 | HTR6 (0.48) | HTR6CYP3A4 | |
| SCHEMBL5334694 | 0.82 | HTR6 (0.48) | HTR6PTGDR2CYP3A4 | |
| SCHEMBL5327681 | 0.82 | HTR6 (0.55) | HTR6CYP3A4 | |
| SCHEMBL5325142 | 0.82 | HTR6 (0.56) | HTR6 | |
| SCHEMBL5327660 | 0.81 | HTR6 (0.59) | HTR6CYP3A4 | |
| SCHEMBL5330688 | 0.81 | HTR6 (0.53) | HTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | claimed |
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |