Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 15/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325138 | 0.87 | HTR6 (0.53) | HTR6CYP3A4 | |
| SCHEMBL5334191 | 0.85 | HTR6 (0.45) | HTR6CYP3A4 | |
| SCHEMBL5330251 | 0.85 | HTR6 (0.50) | HTR6HTR1ACYP3A4 | |
| SCHEMBL5330688 | 0.83 | HTR6 (0.53) | HTR6CYP3A4 | |
| SCHEMBL5331272 | 0.82 | HTR6 (0.53) | HTR6CYP3A4 | |
| SCHEMBL5327720 | 0.82 | HTR6 (0.53) | HTR6CYP3A4 | |
| SCHEMBL5332561 | 0.81 | HTR6 (0.46) | HTR6 | |
| SCHEMBL5330297 | 0.80 | HTR6 (0.52) | HTR6HTR1ACYP3A4 | |
| SCHEMBL5414724 | 0.80 | HTR6 (0.52) | HTR6HTR1ACYP3A4 | |
| SCHEMBL5330101 | 0.80 | HTR6 (0.51) | HTR6CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |