Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.51 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330910 | 0.92 | HTR6 (0.51) | HTR6PTGDR2 | |
| SCHEMBL5328058 | 0.92 | HTR6 (0.49) | HTR6PTGDR2 | |
| SCHEMBL5331429 | 0.90 | HTR6 (0.42) | HTR6PTGDR2POLB | |
| SCHEMBL5330206 | 0.86 | HTR6 (0.48) | HTR6PTGDR2MAPT | |
| SCHEMBL5328966 | 0.86 | PTGDR2 (0.55) | HTR6PTGDR2MAPT | |
| SCHEMBL5329816 | 0.86 | HTR6 (0.41) | HTR6PTGDR2MAPTCA12CA2 | |
| SCHEMBL5332004 | 0.84 | HTR6 (0.58) | HTR6PTGDR2 | |
| SCHEMBL5333545 | 0.84 | HTR6 (0.41) | HTR6PTGDR2MAPTPOLB | |
| SCHEMBL5331545 | 0.84 | HTR6 (0.51) | HTR6 | |
| SCHEMBL5330895 | 0.83 | HTR6 (0.41) | HTR6PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |