Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 9/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5331263 | 0.93 | PTGDR2 (0.44) | HTR6PTGDR2 | |
| SCHEMBL5326887 | 0.91 | HTR6 (0.40) | HTR6PTGDR2 | |
| SCHEMBL5326862 | 0.91 | HTR6 (0.49) | HTR6PTGDR2LMNASMN1; SMN2POLB | |
| SCHEMBL5332248 | 0.89 | HTR6 (0.44) | HTR6PTGDR2ALDH1A1MAPTLMNA | |
| SCHEMBL5328966 | 0.87 | PTGDR2 (0.55) | HTR6PTGDR2MAPTLMNA | |
| SCHEMBL5329816 | 0.85 | HTR6 (0.41) | HTR6PTGDR2MAPT | |
| SCHEMBL5330206 | 0.85 | HTR6 (0.48) | HTR6PTGDR2MAPTLMNA | |
| SCHEMBL5325199 | 0.84 | HTR6 (0.51) | HTR6PTGDR2MAPTPOLB | |
| SCHEMBL5332004 | 0.83 | HTR6 (0.58) | HTR6PTGDR2 | |
| SCHEMBL5424103 | 0.83 | DDR1 (0.35) | HTR6PTGDR2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |