SCHEMBL5325219

SCHEMBL5325219

CC(P(C)(C)=O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.47
LAP3 P28838 4/20 0.43
ANPEP P15144 4/20 0.43
ERAP1 Q9NZ08 1/20 0.43
GABBR2 O75899 1/20 0.36
GABBR1 Q9UBS5 1/20 0.36
FDPS P14324 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
MMP2 P08253 2/20 0.33
METAP1 P53582 1/20 0.33
KDM4E B2RXH2 1/20 0.33
THRB P10828 1/20 0.33
MAPK1 P28482 1/20 0.33
HSD17B10 Q99714 1/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
MMP1 P03956 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230835 0.85 LAP3 (0.47) CA2LAP3ANPEPERAP1FDPS
SCHEMBL12862406 0.83 CA2 (0.44) CA2LAP3ANPEPERAP1GABBR2
Ammonia Solution, Strong SCHEMBL27363837 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
SCHEMBL10940222 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
SCHEMBL27857546 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
SCHEMBL22346009 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
SCHEMBL9539964 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
Methyl Alcohol SCHEMBL11367531 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
SCHEMBL27852339 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS
Water SCHEMBL28284085 0.81 LAP3 (0.45) CA2LAP3ANPEPERAP1FDPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007138381-A2 PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS TARGANTA THERAPEUTICS INC. (CA) 2007-12-06 WO disclosed
US-4401473-A Use of dimethylphosphinylalkanephosphonic acid as a setting retarder in gypsum HOECHST AKTIENGESELLSCHAFT (DE) 1983-08-30 US disclosed
EP-0044470-B1 DIMETHYLPHOSPHINYL-ALKANEPHOSPHONIC ACIDS, PROCESS FOR PREPARING THEM AND THEIR USE AS CEMENT SETTING RETARDANTS HOECHST AKTIENGESELLSCHAFT (DE) 1983-06-15 EP disclosed
EP-0044470-A1 Dimethylphosphinyl-alkanephosphonic acids, process for preparing them and their use as cement setting retardants HOECHST AKTIENGESELLSCHAFT (DE) 1982-01-27 EP disclosed