Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 12/20 | 0.48 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.40 |
| ▸ | ACLY | P53396 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330799 | 0.93 | HTR6 (0.45) | HTR6PTGDR2ACLYLMNA | |
| SCHEMBL5329812 | 0.91 | HTR6 (0.43) | HTR6PTGDR2LMNA | |
| SCHEMBL5420513 | 0.89 | PTGDR2 (0.44) | HTR6PTGDR2PTGDRLMNA | |
| SCHEMBL5332078 | 0.89 | HTR6 (0.53) | HTR6ACLYLMNA | |
| SCHEMBL5329965 | 0.88 | PTGDR2 (0.54) | HTR6PTGDR2PTGDRLMNA | |
| SCHEMBL5327986 | 0.87 | HTR6 (0.52) | HTR6PTGDR2PTGDRLMNA | |
| SCHEMBL5327664 | 0.86 | HTR6 (0.47) | HTR6LMNA | |
| SCHEMBL5331697 | 0.86 | HTR6 (0.55) | HTR6 | |
| SCHEMBL5328556 | 0.85 | HTR6 (0.50) | HTR6PTGDR2PTGDRLMNA | |
| SCHEMBL5331610 | 0.83 | HTR6 (0.52) | HTR6PTGDR2PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |