Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 13/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5332244 | 0.93 | HTR6 (0.47) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5333170 | 0.90 | HTR6 (0.54) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5328011 | 0.89 | HTR6 (0.52) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5330893 | 0.89 | HTR6 (0.43) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5325372 | 0.86 | HTR6 (0.48) | HTR6 | |
| SCHEMBL5330799 | 0.84 | HTR6 (0.45) | HTR6GAA | |
| SCHEMBL5331698 | 0.83 | HTR6 (0.54) | HTR6GAAHPGDALDH1A1L3MBTL1 | |
| SCHEMBL5333542 | 0.82 | MAPT (0.39) | HTR6GAAALDH1A1SMN1; SMN2 | |
| SCHEMBL5420513 | 0.82 | PTGDR2 (0.44) | HTR6 | |
| SCHEMBL5330679 | 0.82 | HTR6 (0.49) | HTR6GAAHPGDALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |