Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 4/20 | 0.62 |
| ▸ | PPARG | P37231 | 4/20 | 0.62 |
| ▸ | MAOB | P27338 | 2/20 | 0.60 |
| ▸ | PPARD | Q03181 | 1/20 | 0.59 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.58 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.58 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.58 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.57 |
| ▸ | LTA4H | P09960 | 2/20 | 0.55 |
| ▸ | MME | P08473 | 1/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.55 |
| ▸ | CPA1 | P15085 | 1/20 | 0.55 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.55 |
| ▸ | LAP3 | P28838 | 1/20 | 0.54 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5323507 | 0.89 | LTA4H (0.62) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL10071090 | 0.85 | FFAR1 (0.67) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL4665082 | 0.85 | FFAR1 (0.67) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL883357 | 0.84 | SLC1A3 (0.63) | NR4A2ACECPA1 | |
| SCHEMBL5511480 | 0.84 | SLC1A3 (0.63) | NR4A2ACECPA1 | |
| SCHEMBL7801265 | 0.83 | PPARA (0.70) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL14501338 | 0.81 | MAOB (0.61) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL14501342 | 0.81 | MAOB (0.61) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL2164145 | 0.80 | PPARG (0.67) | PPARAPPARGMAOBPPARDNR4A1 | |
| SCHEMBL1069493 | 0.80 | PPARG (0.67) | PPARAPPARGMAOBPPARDNR4A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118963-A2 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |