SCHEMBL5325486

SCHEMBL5325486

O=C(O)C1(CN2CCCC2)CCCC1

nearest known ligand 0.48

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.48
MAPK1 P28482 2/20 0.36
KDM1A O60341 1/20 0.36
CYP1A2 P05177 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HRH1 P35367 2/20 0.36
GAA P10253 2/20 0.34
ALDH1A1 P00352 2/20 0.34
POLB P06746 1/20 0.34
MAPT P10636 1/20 0.34
TBXAS1 P24557 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
HTR2A P28223 2/20 0.33
LMNA P02545 1/20 0.33
MME P08473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6226343 0.93 CYP2C19 (0.40) CYP2C19MAPK1KDM1ACYP1A2SMN1; SMN2
SCHEMBL6228575 0.91 CYP2C19 (0.43) CYP2C19MAPK1KDM1ACYP1A2SMN1; SMN2
SCHEMBL5327581 0.84 HRH1 (0.44) CYP2C19KDM1AHRH1HTR2A
SCHEMBL3296864 0.81 CYP2C19 (0.44) CYP2C19KDM1AHRH1TBXAS1KMT2A
SCHEMBL16072551 0.81 ALDH1A1 (0.39) CYP2C19MAPK1CYP1A2SMN1; SMN2GAA
SCHEMBL5325425 0.79 CYP2C19 (0.45) CYP2C19MAPK1CYP1A2SMN1; SMN2GAA
SCHEMBL22629578 0.77 HTR7 (0.40) CYP2C19MAPK1KDM1ACYP1A2GAA
SCHEMBL3296699 0.77 CYP2C19 (0.41) CYP2C19KDM1ACYP1A2SMN1; SMN2ALDH1A1
SCHEMBL5276929 0.76 CYP2C19 (0.40) CYP2C19KDM1AHRH1
SCHEMBL13993938 0.76 ALDH1A1 (0.37) MAPK1CYP1A2SMN1; SMN2GAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO claimed
WO-2007142804-A2 PREPARATION OF COMPLEXING AGENTS AND METAL ION COMPLEXES IN AQUEOUS MEDIA MALLINCKRODT INC. (US) 2007-12-13 WO disclosed