SCHEMBL5325549

SCHEMBL5325549

C=C(C)C(=O)N(C)CCC(C)=O

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
PAOX Q6QHF9 1/20 0.33
LMNA P02545 1/20 0.33
SLC15A2 Q16348 1/20 0.33
CHRM1 P11229 1/20 0.33
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9814628 0.85 TDP1 (0.36) ALDH1A1CHRM1TDP1
SCHEMBL15264026 0.84 PHF8 (0.39) ALDH1A1LMNASLC15A2
SCHEMBL6402859 0.83 TDP1 (0.39) TDP1
SCHEMBL9906112 0.81 TDP1 (0.33) TDP1
SCHEMBL7729369 0.79 CA12 (0.33) PAOXCHRM1TDP1
SCHEMBL4374621 0.79 TDP1 (0.32) TDP1
SCHEMBL375727 0.79 CA12 (0.34) ALDH1A1TDP1
SCHEMBL158624 0.79 MAPT (0.38) TDP1
SCHEMBL10053109 0.77 TDP1 (0.31) TDP1
SCHEMBL8746116 0.77 TRPA1 (0.32) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0611566-B1 Aqueous aerosol lacque for fixing hair OREAL (FR) 1997-05-07 EP claimed
US-5587145-A COPOLYMER CONTAINING UNSATURATED SULFONIC ACID WITH SPECIFIC DEGREE OF NEUTRALIZATION AND N-MONOALKYL(METH)ACRYLAMIDE, DIMETHYL ETHER PROPELLANT L'OREAL (FR) 1996-12-24 US claimed
EP-3068448-A1 MULTILAYER COMPOSITION First Water Limited (GB) 2016-09-21 EP disclosed
EP-3060264-A1 FLEXIBLE HYDROGEL WOUND DRESSINGS First Water Limited (GB) 2016-08-31 EP disclosed
EP-2904038-A1 HYDROGEL COMPOSITES First Water Limited (GB) 2015-08-12 EP disclosed
WO-2015071653-A1 MULTILAYER COMPOSITION FIRST WATER LIMITED (GB) 2015-05-21 WO disclosed
WO-2015059501-A1 FLEXIBLE HYDROGEL WOUND DRESSINGS FIRST WATER LIMITED (GB) 2015-04-30 WO disclosed
WO-2007113453-A1 ABSORBENT HYDROGEL COMPOSITES FIRST WATER LIMITED (GB) 2007-10-11 WO disclosed
US-5587145-A COPOLYMER CONTAINING UNSATURATED SULFONIC ACID WITH SPECIFIC DEGREE OF NEUTRALIZATION AND N-MONOALKYL(METH)ACRYLAMIDE, DIMETHYL ETHER PROPELLANT L'OREAL (FR) 1996-12-24 US disclosed