Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2498409 | 0.93 | PAOX (0.36) | EPHX2 | |
| Hydrochloric Acid SCHEMBL10795220 | 0.91 | PAOX (0.35) | — | |
| SCHEMBL9906096 | 0.91 | EPHX2 (0.30) | EPHX2 | |
| SCHEMBL9814628 | 0.90 | TDP1 (0.36) | TDP1 | |
| SCHEMBL22472120 | 0.89 | ALDH1A1 (0.42) | EPHX2 | |
| SCHEMBL990556 | 0.89 | EPHX2 (0.31) | EPHX2 | |
| SCHEMBL375629 | 0.89 | EPHX2 (0.45) | EPHX2 | |
| SCHEMBL6536053 | 0.88 | EPHX2 (0.32) | EPHX2 | |
| SCHEMBL22472148 | 0.88 | PAOX (0.39) | EPHX2 | |
| SCHEMBL22051805 | 0.88 | EPHX2 (0.35) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DENTSPLY SIRONA INC. (US) | 2024-01-02 | — | — | US | disclosed |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | DENTSPLY SIRONA INC. (US) | 2022-02-03 | — | — | US | disclosed |
| US-11224557-B2 | Dental composition | DENTSPLY SIRONA INC (US) | 2022-01-18 | — | — | US | disclosed |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DENTSPLY SIRONA INC. (US) | 2022-01-06 | — | — | US | disclosed |
| US-11141357-B2 | Dental adhesive | DENTSPLY SIRONA INC. (US) | 2021-10-12 | — | — | US | disclosed |
| US-11116702-B2 | Dental composition | DENTSPLY SIRONA INC. (US) | 2021-09-14 | — | — | US | disclosed |
| US-11110037-B2 | Methods and compositions to stabilize a nanogel and dental compositions therefrom | DENTSPLY SIRONA INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-11110039-B2 | Macromonomer based light-curable dental impression material | DENTSPLY SIRONA INC. (US) | 2021-09-07 | — | — | US | disclosed |
| US-20210137795-A1 | DENTAL ADHESIVE | DENTSPLY SIRONA INC. (US) | 2021-05-13 | — | — | US | disclosed |
| US-20210106503-A1 | DENTAL IMPRESSION MATERIAL | DENTSPLY SIRONA INC. (US) | 2021-04-15 | — | — | US | disclosed |
| US-8546463-B2 | Dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8546463-B2 | Dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2013-10-01 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-8198388-B2 | One-part self-etching, self-priming dental adhesive composition | DENTSPLY INTERNATIONAL INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20100022682-A1 | Dental adhesive composition | KLEE JOACHIM E | 2010-01-28 | — | — | US | disclosed |
| US-20100022682-A1 | Dental adhesive composition | KLEE JOACHIM E | 2010-01-28 | — | — | US | disclosed |
| US-20090043008-A1 | Dental adhesive | KLEE JOACHIM E | 2009-02-12 | — | — | US | disclosed |
| US-20090043008-A1 | Dental adhesive | KLEE JOACHIM E | 2009-02-12 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | DENTSPLY DE TREY GMBH (DE) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11224557-B2 | Dental composition | GPX4, GPX1, NOXO1 | TDP1 2950/4885EPHX2 137/4885 |
| US-11141357-B2 | Dental adhesive | CDH1, ITGA5, ICAM1 | TDP1 1425/4885EPHX2 50/4885 |
| US-20220000721-A1 | BIFUNCTIONAL AND POLYFUNCTIONAL COINITIATORS IN DENTAL COMPOSITIONS | DUOX2, DUOX1, QSOX1 | TDP1 306/4885EPHX2 70/4885 |
| US-20210106503-A1 | DENTAL IMPRESSION MATERIAL | FHIT, PASK, TAS2R40 | TDP1 2550/4885EPHX2 3654/4885 |
| US-11110039-B2 | Macromonomer based light-curable dental impression material | EPM2A, LMNB1, LMNB2 | TDP1 2240/4885EPHX2 585/4885 |
| US-20210137795-A1 | DENTAL ADHESIVE | CDH1, ITGA5, ICAM1 | TDP1 1425/4885EPHX2 50/4885 |
| US-11857650-B2 | Dental composition comprising a dental filler containing a structural filler and silanated glass flakes | DHX35, DHX30, FLNA | TDP1 2619/4885EPHX2 474/4885 |
| US-11110037-B2 | Methods and compositions to stabilize a nanogel and dental compositions therefrom | TSG101, WASF2, RAB5IF | TDP1 631/4885EPHX2 444/4885 |
| US-11116702-B2 | Dental composition | MTR, CAD, PAM | TDP1 2994/4885EPHX2 185/4885 |
| US-20070293642-A1 | One-Part Self-Etching, Self-Priming Dental Adhesive Composition | CAD, ASIC1, PDAP1 | TDP1 2572/4885EPHX2 134/4885 |
| US-20090043008-A1 | Dental adhesive | H1-0, H1-2, ITGA1 | TDP1 3323/4885EPHX2 169/4885 |
| US-20220031576-A1 | ADDITIVE MANUFACTURING PROCESS | FLNA, FLNB, SAMM50 | TDP1 3340/4885EPHX2 2852/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.