Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 3/20 | 0.68 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5324773 | 1.00 | SLC2A1 (0.68) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL14399139 | 1.00 | SLC2A1 (0.68) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5320726 | 0.89 | SLC2A1 (0.54) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5323536 | 0.89 | SLC2A1 (0.54) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL14397306 | 0.89 | SLC2A1 (0.54) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL14398545 | 0.89 | SLC2A1 (0.53) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL14398255 | 0.89 | SLC2A1 (0.53) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL6933526 | 0.82 | SLC2A1 (0.68) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL6931984 | 0.80 | SLC2A1 (0.65) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 | |
| SCHEMBL5623473 | 0.80 | SLC2A1 (0.65) | SLC2A1KCNH2SMN1; SMN2THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | claimed |
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |
| WO-2007121415-A2 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-10-25 | — | — | WO | disclosed |