Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.42 |
| ▸ | MC5R | P33032 | 1/20 | 0.42 |
| ▸ | MC3R | P41968 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 3/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5321280 | 0.92 | ICMT (0.46) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5326617 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5325121 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5329767 | 0.92 | MAPT (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5321455 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5328167 | 0.92 | MAPT (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5324911 | 0.91 | ICMT (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5330027 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5415056 | 0.91 | SMN1; SMN2 (0.45) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL5389491 | 0.90 | ALDH1A1 (0.44) | ALDH1A1MAPTSMN1; SMN2LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115231-A2 | CXCR4 MODULATORS | CHEMOCENTRYX, INC. (US) | 2007-10-11 | — | — | WO | disclosed |