Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 13/20 | 0.41 |
| ▸ | CCKBR | P32239 | 7/20 | 0.36 |
| ▸ | CCKAR | P32238 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5352183 | 0.77 | PTH1R (0.36) | PTH1R | |
| SCHEMBL5354276 | 0.77 | PTH1R (0.34) | PTH1RCCKBRCCKAR | |
| SCHEMBL5320870 | 0.76 | PDE4B (0.42) | PTH1R | |
| SCHEMBL5351487 | 0.76 | PTH1R (0.36) | PTH1R | |
| SCHEMBL5325236 | 0.75 | PTH1R (0.46) | PTH1R | |
| SCHEMBL5356554 | 0.74 | PTH1R (0.67) | PTH1R | |
| SCHEMBL5349032 | 0.72 | PTH1R (0.49) | PTH1R | |
| SCHEMBL5355040 | 0.71 | PTH1R (0.39) | PTH1RCCKBRCCKAR | |
| SCHEMBL5361939 | 0.70 | PDE4A (0.40) | PTH1RCCKBR | |
| SCHEMBL5362739 | 0.69 | PTH1R (0.35) | PTH1RCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |