Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 5/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CCKBR | P32239 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CCKAR | P32238 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5362739 | 0.81 | PTH1R (0.35) | PTH1RCCKBRCCKAR | |
| SCHEMBL5326023 | 0.77 | PTH1R (0.37) | PTH1RBRD4CCKBR | |
| SCHEMBL5355357 | 0.77 | BRD4 (0.36) | PTH1RBRD4ALDH1A1CCKBR | |
| SCHEMBL5355360 | 0.77 | BRD4 (0.36) | PTH1RBRD4ALDH1A1CCKBR | |
| SCHEMBL5358455 | 0.76 | BCHE (0.37) | PTH1RALDH1A1CCKBR | |
| SCHEMBL5321928 | 0.76 | ALDH1A1 (0.35) | PTH1RALDH1A1CCKBR | |
| SCHEMBL5355386 | 0.74 | ALDH1A1 (0.36) | PTH1RALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL5329713 | 0.73 | PTH1R (0.45) | PTH1RALDH1A1CCKBR | |
| SCHEMBL5353466 | 0.72 | PTH1R (0.54) | PTH1R | |
| SCHEMBL5323349 | 0.72 | ALDH1A1 (0.34) | PTH1RALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007135417-A1 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-11-29 | — | — | WO | disclosed |