Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.67 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.61 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.56 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8420401 | 1.00 | LTB4R (0.67) | LTB4RLTB4R2MAOBNR1H4NR4A1 | |
| SCHEMBL5326284 | 1.00 | LTB4R (0.67) | LTB4RLTB4R2MAOBNR1H4NR4A1 | |
| SCHEMBL11175800 | 0.88 | MEN1 (0.57) | LTB4RLTB4R2MAOBNR1H4NR4A1 | |
| SCHEMBL11175805 | 0.88 | MEN1 (0.57) | LTB4RLTB4R2MAOBNR1H4NR4A1 | |
| SCHEMBL11158616 | 0.86 | MAOB (0.64) | LTB4RLTB4R2MAOBNR1H4NR4A2 | |
| SCHEMBL11158605 | 0.86 | MAOB (0.64) | LTB4RLTB4R2MAOBNR1H4NR4A2 | |
| SCHEMBL14021555 | 0.86 | MAOB (0.64) | LTB4RLTB4R2MAOBNR1H4NR4A2 | |
| SCHEMBL5078615 | 0.83 | MAPT (0.51) | L3MBTL1LMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2205707 | 0.83 | MAPT (0.51) | L3MBTL1LMNAALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL2205704 | 0.83 | MAPT (0.51) | L3MBTL1LMNAALDH1A1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007118964-A1 | SUBSTITUTED N-(PHENETHYL)BENZAMIDE DERIVATIVES, PREPARATION AND USES THEREOF | GENFIT (FR) | 2007-10-25 | — | — | WO | disclosed |